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Menstrually Related Mood Disorders Screening

University of North Carolina at Chapel Hill


The primary purpose is to provide a mechanism for identifying patients with menstrually-related mood disorder (MRMD) who can participate in a variety of separate protocols. Those diagnosed with MRMD will be invited to participate in additional companion protocols.


Behavior, Mental Health, Women's Health





18 - 52 years


Study Population

Medically healthy women ages 18-52 with regular menses (cycle length from 21 to 35 days) who experience mood symptoms the week before menstruation.


Susan Girdler
Psychiatry - Research

For questions, contact:

Tara Rana
(919) 537-9352
Visit Website

Recruitment Period End

February 1, 2025


Primary Location
Carolina Crossing Building B, Suite 1
2218 Nelson Hwy, Chapel Hill, NC 27517, USA
Secondary Location
Medical School Wing D
Medical School Wings, Chapel Hill, NC 27514, USA

Study Qualifications

Gender Female

Age Range 18 - 52 years

Participant qualification(s) - Female - Age 18-52 - Not pregnant or lactating - In good medical health - Regular menses (which cycle length may vary, 28 days is generally taken as representative of the average menstrual cycle in women; the range may be from 21-35 days) - Experiencing menstrually-related mood or behavioral disturbances

Not eligible if: - Use of medications that affect mood, cognition, or the menstrual cycle (such as antidepressants, benzodiazepines, or hormonal medications such as birth control) - Current Axis I psychiatric disorders - Significant renal, cardiac, hepatic, or other medical disorder

Number of Visits

    » 1-2 In person visit(s)

    1 screening/enrollment visit; 1 clinic visit

    » 2 Remote visit(s)

    2 phone check-ins, if necessary

Participation Period

3-5 months


$25 check for Visit 2

By clicking I am interested, your contact information will be sent to the researcher/study coordinator for this study. The coordinator will respond by email with additional information on how to proceed.