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Brain circuits for behavioral flexibility and adolescent alcohol use

University of North Carolina at Chapel Hill


To test for an association between individual tendency toward habitual actions and sensitivity to reward conditioning, whether connections between certain brain areas predict the association between these behaviors, and how these factors are influenced by adolescent alcohol history.


Alcohol Abuse, Behavior, Brain/Head, Substance/Drug Use





22 - 40 years


Study Population

Healthy adults ages 22-40 who either did or did not engage in binge drinking before age 18.


Charlotte Boettiger
Associate Professor
Psychology and Neuroscience

For questions, contact:

Samantha Dove
(919) 843-9193
Visit Website

Recruitment Period End

November 30, 2022


Primary Location
103 Howell Hall
Chapel Hill, NC 27514, USA
Secondary Location
Biomedical Research Imaging Center
Marsico Hall, Chapel Hill, NC 27599, USA

Study Qualifications

Gender Any

Age Range 22 - 40 years

Participant qualification(s) - high school educated - medically healthy - 22-40 years old - native-English speaker - high levels of adolescent binge alcohol exposure (≥4 binge drinking episodes before age 18; AIE) OR no adolescent binge alcohol exposure

Not eligible if: -Under 22 years old -Over 40 years old -Any known neurological disorders such as dementia, seizures or head trauma -Any known psychiatric disorders such as depression or psychosis Current use of any psychoactive medications (e.g. antidepressants or narcotic pain relievers) -Current illicit drug use -No lifetime history of an substance use disorder (including nicotine) but AIE participants will not be excluded for an alcohol use disorder - no systemic disease such as cancer, cardiovascular or inflammatory disease which could influence cognitive functioning - no motor or visual disturbance (including color blindness) which precludes them from performing the tasks -Non native English speaker -No high school diploma or equivalent -Electrically, magnetically or mechanically activated implants (such as cardiac pacemakers) -Surgically implanted metal clips in any blood vessels within your brain -Metal in your body that you cannot take out, Tattoos above the shoulders -Currently pregnant -Left handed -Claustrophobia (fear of enclosed spaces) - no lifetime nicotine dependence

Number of Visits

    » 2 In person visit(s)

    1 Screening & Training, 1 MRI scan

    » 1 Remote visit(s)

    1 Online Survey

Participation Period

3 weeks


$15 per hour (about 6 hours total)

By clicking I am interested, your contact information will be sent to the researcher/study coordinator for this study. The coordinator will respond by email with additional information on how to proceed.