Individuals with a history of anterior cruciate ligament reconstruction (ACLR) are at a heightened risk for developing osteoarthritis. The heightened risk for developing osteoarthritis is likely caused by either too much force or too little force applied to the knee during tasks such as walking. In order to develop effective treatments that can change the force applied to the knee during walking, we must first determine what amount of force is beneficial for the knee following ACLR. The purpose of this research study is to determine if feedback about the force applied to each leg during walking can be used to alter force while walking. The feedback used in this study will display targets for average force, high force and low force. We will then determine the effect of average force, high force and low force on lower extremity movement patterns and markers of cartilage turnover and inflammation. You will be asked to complete 1 screening session (1.5 hours) and four testing sessions, with one week in between each session. Each testing session will last approximately 5 hours, (most of this time you will be sitting) therefore the entire duration of the study will be 21.5 hours over 5 weeks. If you choose to take part in the study you will complete the same assessments in the same order during each testing session. The assessments include: questionnaires, activity monitoring, blood draws, gait biomechanics assessment, and a walking biofeedback intervention.
Bones, Joints, Muscles, Pain, Pediatrics, Teens
Drug or Biologic