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COPD Trial to Reduce Exacerbations

University of North Carolina at Chapel Hill


The goal of this study is to understand if an investigational medication reduces the number of exacerbations you have in a year. Participants will either be given the active medication or a placebo (inactive solution that does not contain medication) as an injection given every two weeks in clinic for one year.


Breathing, Lungs, Smoking


Drug or Biologic



40 - 75 years


Study Population

Patients who have been diagnosed with moderate to severe COPD and have been on inhalers and are still not well controlled. Eligible participants should be between the ages of 40 to 75, on daily inhalers, and have had at least one breathing flare in the past year.


Brad Drummond
Associate Professor

For questions, contact:

Karen Hardy
(984) 974-2971

Recruitment Period End

July 31, 2019


Primary Location
Pulmonary Research Unit at Meadowmont
Meadowmont Village Cir, Chapel Hill, NC 27517, USA

Study Qualifications

Gender Any

Age Range 40 - 75 years

Participant qualification(s) Age 40 to 75 Diagnosed with COPD, emphysema, or chronic brochitis on daily inhalers History of two or more flares of COPD

Not eligible if: Active tuberculosis (TB) Oxygen use for more than 15 hours per day Prior surgery to remove part of the lung Females who are currently pregnant or breastfeeding

Number of Visits

    » 29 In person visit(s)

    1 Screening, 1 Randomization, 28 Clinic

    » 1 Remote visit(s)


Participation Period



Up to $2,260

By clicking I am interested, your contact information will be sent to the researcher/study coordinator for this study. The coordinator will respond by email with additional information on how to proceed.