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In-vivo effects of E-cigarette aerosol

University of North Carolina at Chapel Hill


To determine if e-cigarettes with Cinnamaldehyde (Cinnamon) flavoring impact the epithelial cell function as measured by mucociliary clearance (MCC)


Behavior, Breathing, Lungs, Smoking





18 - 40 years


Study Population

Adult females ages 18-40 that use an e-cigarette device.


Ilona Jaspers
Pediatrics - Allergy Immunology and Rheumatology

For questions, contact:

Carole Robinette
(919) 843-8472

Recruitment Period End

October 23, 2023


Primary Location
Center for Environmental Medicine, Asthma, and Lung Biology
104 Mason Farm Rd, Chapel Hill, NC 27514, USA

Study Qualifications

Gender Female

Age Range 18 - 40 years

Participant qualification(s) You may be eligible if you are 18-40 and currently use an e-cigarette device.

Not eligible if: You are not eligible to participate if you have: pre-existing lung disease (e.g., asthma, cystic fibrosis, etc.), significant chronic illness (such as, but not limited to, heart disease, uncontrolled hypertension, diabetes, auto-immune disease), have used any kind of tobacco product (other than e-cig) in the past 3 months, have ever smoked more than 10 packs in a year, if you are pregnant or nursing, or if you have had regular CT scans or x-rays over the past year.

Number of Visits

    » 7 visits In person visit(s)

    (0) Screening; (1) Baseline Measurements; (2) Follow-Up/Training; (3) Scan/Vape day; (4) Follow-up; (5) Crossover scan/vape; (6) Follow-up

    » 0 Remote visit(s)

Participation Period

About 3 months


$750 for completing all study visits and activities

By clicking I am interested, your contact information will be sent to the researcher/study coordinator for this study. The coordinator will respond by email with additional information on how to proceed.