In-vivo effects of E-cigarette aerosol
University of North Carolina at Chapel Hill
Description
To determine if e-cigarettes with Cinnamaldehyde (Cinnamon) flavoring impact the epithelial cell function as measured by mucociliary clearance (MCC)
Keywords:
Behavior, Breathing, Lungs, Smoking
Category:
Procedures
Qualifications
Age
18 - 40 years
Gender
Any
Study Population
Adults ages 18-40 that use an e-cigarette device. Adults ages 18-40 that DO NOT use an e-cigarette device.
Investigator
Ilona Jaspers
Professor
Pediatrics - Allergy Immunology and Rheumatology
Recruitment Period End
October 23, 2023
Location
Primary Location
Center for Environmental Medicine, Asthma, and Lung Biology
104 Mason Farm Rd, Chapel Hill, NC 27514, USA
Study Qualifications
Age Range 18 - 40 years
Participant qualification(s) Subjects who currently use an e-cigarette device. -and/or- Subjects who do not use an e-cigarette device. Ages 18-40 Acceptable pulmonary function as measured in our lab
Not eligible if: Any pre-existing lung disease (e.g., asthma, cystic fibrosis, etc.) Any significant chronic illness, such as, but not limited to, heart disease, uncontrolled hypertension, diabetes, auto-immune disease Any use of tobacco products (other than e-cig) in the past 3 months, or a greater than 10 pack year history of smoking cigarettes. Pregnant or nursing women Subjects with a history of radiation exposure in the past year which exceeds annual safe limits.
Number of Visits
- » 3 visits for the control cohort, 7 visits of the vaping cohort In person visit(s)
The contorl cohort (non-vapers) will have three visits that will consist of a (1) Screening visit, (2) baseline measurement, and (3) follow up visit. The vaping cohort will have the same first three visits as well as (4) Scan/Vaping visit, (5) Follow up visit. Visits (6) and (7) will occur after the crossover period.
» 0 Remote visit(s)Participation Period
Aproximatley two months